Is the West Virginia/Louisville "unbeaten" showdown an inevitability, or will one or both of them be knocked off before then?

Louisville has Cincinnati, Syracuse and a bye week before the October 2 showdown.  West Virginia must face Syracuse and Connecticut but also has a bye week immediately preceding the game.

Survey probably says... no.

However, what happens after the game could be much more dramatic.  If either team suffers some kind of big game hangover, they could be picked off.

West Virginia gets to fatten up on Cincinnati afterwards, but then finishes with the meat of the Big East in Pittsburgh (road), South Florida and Rutgers.

Louisville faces the same three teams, but with a roadie to Rutgers immediately following the big game.  Could be trouble there.

There's just something to playing an anticipated, dramatic game that teams often have hangovers or hiccups afterwards.  Louisville must be particularly mindful as Rutgers will be particularly feeling good about itself (possible 8-0) and inspired to pull a home upset.